Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC
نویسندگان
چکیده
Sulforaphane modulates microRNA expression in colon cancer cells to 1 implicate the regulation of oncogenes CDC25A, HMGA2 and MYC. 2 Christopher A. Dacosta, Claudia Paicu, Irina Mohorianu, Wei Wang, Ping Xu, Tamas 3 Dalmay, Yongping Bao 4 Norwich Medical School, University of East Anglia, Norwich, NR4 7UQ, UK 5 School of Computing Sciences, University of East Anglia, Norwich, NR4 7TJ, UK 6 School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK 7 *Requests for reprints: Yongping Bao, Norwich Medical School, University of East Anglia, 8 Norwich, NR4 7UQ, UK. Tel: +44 1603 591778; E-mail: [email protected] 9 Running Title: SFN against colorectal cancer: potential roles of miRNAs. 10
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STUDY OF HMGA2 GENE INHIBITION WITH SPECIFIC SHRNA AND SIRNA AND INVESTIGATION OF CORRESPONDING EFFECTS ON DOWNSTREAM GENE EXPRESSION IN MDA-MB-231 CANCER CELLS: A BIOINFORMATIC AND EXPERIMENTAL STUDY
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